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KMID : 0043319920150010020
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Archives of Pharmacal Research
1992 Volume.15 No. 1 p.20 ~ p.29
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Effects of Squalene on the Immune Responses in Mice(II): Cellular and Non-specific Immune Response and Antitumor Acitivity of Squalene
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Ahn YK
Kim JH
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Abstract
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Effects of squalene on cellular and non-specific immune responses and antitumor activity in mice were investigated. Cellular and non-specific immunological assay parameters adopted in the present study were delayed-type hypersensitivity reaction and rosette forming cells (RFC) for cellular immunity, activities of natural killer (NK) cells and phagocyte for non-specific immunity. Squalene resulted in marked increases of cellular and non-specific immune functions and enhancement of host resistance to tumor challenge in dose-dependent manner.
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KEYWORD
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